Endometrium

Comprehensive Endometrial Assessment: Optimizing Reproductive Success Through Molecular Insights

The endometrium plays a critical role in reproductive success, yet endometrial dysfunction remains one of the most challenging areas in fertility medicine.

Portfolio

Prequel Genetics offers a comprehensive portfolio of advanced molecular diagnostics that provide actionable insights for clinicians treating:

Recurrent implantation failure (RIF)
Unexplained infertility
Endometriosis
Recurrent pregnancy loss
Poor IVF/ART outcomes

Our endometrial testing solutions combine cutting-edge molecular analysis with practical clinical utility, enabling personalized treatment strategies that improve patient outcomes.

Why Endometrial Testing Matters

The Hidden Factor in Fertility: While much attention in fertility treatment focuses on embryo quality and ovarian response, the endometrial environment is equally critical for reproductive success. Research shows:

30-50% of implantation failures are attributed to endometrial factors
Window of implantation displacement occurs in 25-30% of RIF patients
Endometrial dysbiosis correlates with significantly lower implantation rates
Chronic endometritis present in 14-30% of infertile women
Endometriosis affects 10% of women but takes 7-10 years to diagnose
Immune dysfunction contributes to both implantation failure and pregnancy loss

Traditional IVF protocols often overlook endometrial optimization, resulting in repeated cycles without addressing underlying factors. Our molecular diagnostics enable targeted interventions that improve outcomes while reducing emotional and financial burden on patients.

MiFert&i

Endometrial Assessment - three critical analyses:

MiFert Receptivity
The endometrium must be in the receptive phase when the embryo arrives

MiFert Microbiome
The correct balance of beneficial bacteria must be present

MiFert Immunology
The maternal immune system must properly tolerate the embryo

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NDOM – Non-Invasive Endometriosis Detection

Revolutionary blood-based endometriosis screening
93.3% diagnostic accuracy
<5 working days results
Eliminates diagnostic delay (average 7-10 years)
Avoids invasive laparoscopy for diagnosis
University of Oviedo licensed technology

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Clinical Impact:

Our endometrial solutions address the fastest-growing segment of reproductive medicine, supporting IVF clinics, fertility specialists, and gynecologists in delivering evidence-based, personalized care.